李晓 女， 上海血液病研究所副所长；上海市血液分会委员；中华血液杂志编委；白血病.淋巴瘤杂志编委；博导，教授，主任医师；多年从事血液学临床工作和基础研究，对各种血液科疾病的诊断和治疗具备丰富经验。近年主要从事血液系统 常见的恶性疾病骨髓增生异常综合征（MDS）的发病机制与临床诊治的研究。曾两次前往美国 的血液病研究及移植中心进行共同研究及交流。近年来获得多项科研资助，获得上海市科技进步奖2项。以 作者或通讯作者身份发表SCI论著18篇(总影响因子37.638)。2007/2008年度获上海市三八红旗手称号。
曾经和正在进行的重要课题
李晓等.三氧化二砷/TRAIL作为MDS治疗新药的临床前期研究
(上海市科委重点项目2004)( 044119630)
李晓等. MDS和急性髓细胞白血病恶性克隆细胞生物学特性研究
(上海市科委登山计划2006)(064119635)
李晓等参与--骨髓增生异常综合症的规范化诊断与治疗策略
（国家“十一五”科技支撑计划2008BAI61B02）
李晓等.骨髓增生异常综合征的规范化诊断与分层治疗
（申康集团适宜技术应用项目SHDC12010202）
已获得奖项
李晓等 2005年上海市科技进步叁等奖（2005093037）
李晓等《骨髓增生异常综合征发病机制和规范诊治的相关研究 》 2010年上海市科技进步叁等奖（20104387-3-D01）
SCI论著（通讯作者）
1. He Qi, Li Xiao, Wu Lingyun et al. Expression of type 1 insulin-like growth factor receptor in marrow nucleated cells in malignant hematological disorders: correlation with apoptosis. Ann Hematol. 2006; 85(2):95-101.
2. Wu Lingyun, Li Xiao, Chang Chunkang, et al. Deviation of type I and type II T cells and its negative effect on hematopoiesis in myelodysplastic syndrome. Int J Lab Hematol 2008;30(5):390-399
3. Wu Lingyun, Li Xiao, Su Jiying, et al. Effect of low-dose cytarabine, homoharringtonine and granulocyte colony-stimulating factor priming regimen on patients with advanced myelodysplastic syndrome or acute myeloid leukemia transformed from myelodysplastic syndrome. Leukemia Lymphoma, 2009; 50(9): 1461–1467
4. Xu Li, Chang Chunkang, Li Xiao,et al. Appropriate Timing of G-CSF Use After Mobilization Chemotherapy Significantly Increases the Yield of CD341 Cells in autoPBSCT . J Clin Apheresis 2009,6;24(6):232-237.
5. Xu Feng, Li Xiao, Wu Lingyun, et al. Flow cytometric scoring system (FCMSS) assisted diagnosis of myelodysplastic syndromes (MDS) and the biological significance of FCMSS-based immunophenotypes. Br J Haematol. 2010;149 (4):587-97.
6. Zhang Zheng, Zhang Qianqiao, He Qi, Li Xiao,et al. In vitro deprivation
Of CD8CD57 T cells promotes the malignant growth of bone marrow
Colony cells in patients with ower-risk myelodysplastic syndrome .Exp Hematol 2010; 38:677–684
7. He Qi,Li Xiao, Zhang Zheng, et al. Overexpression of IGF-IR in Malignant Clonal Cells in Bone Marrow of Myelodysplastic Syndromes Cancer Invest, 2010；28:983–988
8. Zhang Zheng, Xu Feng, Li Xiao, et al. Removal of autologous activated CD4-positive T lymphocytes also results in increased colony-forming units in patients with low and intermediate-1 risk myelodysplastic syndromes. Eur J Haematol,2011；86 (47–56)
9. Xu Feng,Li Xiao, Wu Lingyun，et，al. Overexpression of the EZH2,
RING1 and BMI1 genes is common in myelodysplastic syndromes:
relation to adverse epigenetic alteration and poor prognostic scoring
Ann Hematol 2011,90:643–653
10. Wu Lingyun, Li Xiao, Su Jiying, et al. Efficacy and safety of CHG
regimen (low-dose cytarabine,homoharringtonine with G-CSF
priming) as induction chemotherapy for elderly patients with
high-risk MDS or AML transformed from MDS J Cancer Res Clin
Oncol (2011) 137:1563–1569
SCI论著（ 作者）
11.Li Xiao, Eileen Bryant, H. Joachim Deeg. Simultaneous Demonstration of Clonal Chromosome Abnormalities and Apoptosis in Individual Marrow Cells in Myelodysplastic Syndrome. Int J Hematol 2004; 80(2): 140—145.
12. Li Xiao & Pu Quan. Megakaryocytopoiesis and apoptosis in patients
with myelodysplastic syndromes. Leukemia Lymphoma 2005;46(3):
387-391.
13.Li Xiao Wu Lingyun, Ying Shaoxu, et al. Wilmms’ tumor gene (WT1) is predominantly expressed in clonal hematopoietic cells in myelodysplastic syndromes. Leukemia Lymphoma 2007; 48[3]: 601-604.
14.Li Xiao, Wu Lingyun, Ying Shaoxu, et al. Differentiation and
hematopoietic-support of clonal cells in myelodysplastic syndromes.
Leukemia Lymphoma 2007；48[7]：1353 – 1371
15.Li Xiao, Wu Lingyun, Ying Shaoxu, et al. Clonality investigation of
morphologically dysplastic hematopoietic cells in myelodysplastic
syndrome marrows. Int J Hematol. 2008; 87(2):176-83.
16.Li Xiao, Song Luxi, Tao Ying, et al. Diagnosis of unknown nonhematological tumors by bone marrow biopsy: a retrospective analysis of 10,112 samples. J Cancer Res Clin Oncol 2009; 135:687–693
17.Li Xiao，Liao Qiong，Zhang yan et al. Experimental and clinical
characteristics in myelodysplastic syndrome patients with or
without HLA-DRI5 allele. Hematol Oncol. 2010; 28:98-103.
18. Li Xiao, Xu Feng, He Qi, et al. Comparison of Immunological Abnormalities of Lymphocytes in Bone Marrow in Myelodysplastic Syndrome (MDS) and Aplastic Anemia (AA). Inter Med 2010 49:1349-1355
个人简介：
李晓 女， 上海血液病研究所副所长；上海市血液分会委员；中华血液杂志编委；白血病完整介绍>>
